华中师范大学学报（自然科学版）2011，Vol.45Issue(3)：421-425,5.
微波辅助三分子点击化学合成1,4-二取代-1,2,3-三氮唑衍生物
A microwave-assisted three molecule click chemistry synthesis of 1,4-disubstituted-1,2,3-triazole derivatives
摘要
Abstract
Triazole is an important organic compound. In this article, we synthesised 1, 4-disubstituted-l, 2, 3-triazole derivatives with click chemistry. A microwave-assisted three-component reaction was used to prepare a series of 1, 4-disubstituted-l, 2, 3-tria-zoles from corresponding sodium azide, alkynes and benzene sulfonates via Cul catalyzed. Controling microwave power 65～80 W, temperature 50～75℃, the reaction was completed in 15 min, the yield of 81%～94%. The structure of new products(e～p) was confirmed by IR、1H NMR、13C NMR、DEPT、HR-MS、elementary analysis. The results indicated that the reaction simple and under mild conditions, and it was environmentally friendly.关键词
1,4-二取代-1,2,3-三氮唑/点击化学/微波合成Key words
1,4-disubstituted-l, 2,3-triazoles/ click chemistry/ microwave synthesis分类
化学化工引用本文复制引用
李海根,熊知行..微波辅助三分子点击化学合成1,4-二取代-1,2,3-三氮唑衍生物[J].华中师范大学学报（自然科学版）,2011,45(3):421-425,5.基金项目
江西省高校重点实验室科技计划项目(赣财教GJJ[2007]431). （赣财教GJJ[2007]431）
