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动物GH/IGF-Ⅰ轴调控机制的研究进展

顾志良 王慧娟 郁建锋

中国畜牧兽医2011,Vol.38Issue(10):50-54,5.
中国畜牧兽医2011,Vol.38Issue(10):50-54,5.

动物GH/IGF-Ⅰ轴调控机制的研究进展

Advances on the Regulation Mechanism of Growth Hormone/IGF- Ⅰ Axis

顾志良 1王慧娟 1郁建锋2

作者信息

  • 1. 常熟理工学院生物与食品工程学院,江苏常熟215500
  • 2. 苏州大学基础医学与生物科学学院,江苏苏州 215123
  • 折叠

摘要

Abstract

The growth axis is a neuroendocrine system, which is composed of series of hormones and their receptors from the hypothalamus-pituitary-target organ in xrivo of animals. Increasing the GH and IGF- I levels in the growth axis, to promote weight gain, feed conversion rate and improve meat quality, which is a new approach of animal growth regulation. GH mediated by IGF- I regulates animal growth and cell differentiation. We will discuss the constitution and function of GH/IGF-I axis, and mechanism of growth hormone regulation of IGF- I expression in this review.

关键词

生长激素/IGF-Ⅰ基因/表达调控

Key words

growth hormone/IGF-I gene/regulation of gene expression

分类

生物科学

引用本文复制引用

顾志良,王慧娟,郁建锋..动物GH/IGF-Ⅰ轴调控机制的研究进展[J].中国畜牧兽医,2011,38(10):50-54,5.

基金项目

国家自然科学基金项目 (31072025)资助. (31072025)

中国畜牧兽医

OA北大核心CSTPCD

1671-7236

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