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淀粉样物质结构的研究方法

张思明 谭荣荣 赵德明 杨利峰

中国畜牧兽医2011,Vol.38Issue(10):217-220,4.
中国畜牧兽医2011,Vol.38Issue(10):217-220,4.

淀粉样物质结构的研究方法

Techniques to Study the Structure of Amyloid

张思明 1谭荣荣 1赵德明 1杨利峰1

作者信息

  • 1. 中国农业大学动物医学院,北京 100193
  • 折叠

摘要

Abstract

Interest in understanding the structural basis of amyloid formation has been strongly motivated by their association with a number of diseases, such as Alzheimer's (AD), Parkinson's, and prion diseases. However, the structure of amyloid is still not very clear. Here, we described some of the most commonly used techniques, such as hydrogen-deuterium exchange, cryoelectron microscopy and solid-state nuclear magnetic resonance, employed in amyloid structure characterization. These techniques enabled high-resolution insights into molecular organization of amyloid.

关键词

纤维样淀粉物质/固态核磁共振/氢氘交换

Key words

amyloid/solid-state NMR/hydrogen-deuterium exchange

分类

农业科技

引用本文复制引用

张思明,谭荣荣,赵德明,杨利峰..淀粉样物质结构的研究方法[J].中国畜牧兽医,2011,38(10):217-220,4.

中国畜牧兽医

OA北大核心CSTPCD

1671-7236

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