河北医学2011，Vol.17Issue(12)：1570-1573,4.DOI:10.3969/j.issn.1006-6233.2011.12.03
高氧液治疗急性脑梗塞疗效观察及抗氧化损伤作用的研究
Effect of Hyperoxia Solution on Anti-oxidative Damage and Clinical Observation on Patients with Acute Cerebral Infarction
刘亚军 1郭义霖1
作者信息
- 1. 成都大学附属医院内科,四川成都610081
- 折叠
摘要
Abstract
Objective; To study the anti-oxidative damage effect of hyperoxia solution on patients with acute cerebral infarction. Method; 58 patients with acute cerebral infarction were randomly divided into hyperoxia solution therapy group and normal therapy control group. Each group was drawn blood and the SOD, MDA and NO concentration of blood plasma was measured according to the kit protocol before and 24h, 48 h after therapy. Meanwhile the clinical curative effect during the therapy was evaluated by the NDS standard. Result: The SOD concentration of blood plasma in hyperoxia solution therapy group remarkably rised and the MDA, NO concentration of blood plasma remarkably decreased after therapy. There was significant difference between the two group(P ＜ 0. 05) in the concentration contrast of SOD, MDA, and NO during the therapy. The NSD score in hyperoxia solution therapy group was lower than the control group (P ＜ 0. 05). Conclusion ; Hyperoxia solution may relieve ischemical reperfusion injury in acute cerebral infarction by means of e-liminating oxygen free radical and anti-oxidative damage.关键词
高氧液/急性脑梗塞/抗氧化损伤Key words
Hyperoxia solution/ Acute cerebral infarction/ Anti-oxidative damage引用本文复制引用
刘亚军,郭义霖..高氧液治疗急性脑梗塞疗效观察及抗氧化损伤作用的研究[J].河北医学,2011,17(12):1570-1573,4.
