烟台大学学报（自然科学与工程版）2011，Vol.24Issue(4)：264-270,7.
焦脱镁叶绿酸-α甲酯的二氢卟吩色基上的官能团的修饰与保护
Modification and Protection for Functional Groups on Chlorin Chromophore of Mthyl Pheophorbide-α
摘要
Abstract
Methyl pyropheophorbide-a is obtained from chlorophyll-a by the reflux in acetic acid for weeding out center magnesium ion and removing carbomethoxyl group in one step and the methylation with diazometh-ane. The active reaction sites of methyl pyropheophorbide-a, including C3-vinyl group, C132-carbonyl group, terminal C17-carbonmethoxyl group and C20-meso-hydrogen, are protected by electrophilic addition, electro-philic substitution, nucleophilic addition, oxidation, reduction and elimination reactions. The protecting processes for these functional group are discussed and the reaction mechanisms are tentatively proposed. The structures of all new compounds are assigned based on the data from IR, 1HNMR, MS and elemental analysis.关键词
叶绿素-α/二氢卟吩/脱镁叶绿酸-α甲酯/官能团保护Key words
chlorophyll-a/ chlorin/ methyl pheophorbide-a/ protection of functional group分类
化学化工引用本文复制引用
武进,刘冉冉,杨泽,王振,王进军..焦脱镁叶绿酸-α甲酯的二氢卟吩色基上的官能团的修饰与保护[J].烟台大学学报（自然科学与工程版）,2011,24(4):264-270,7.基金项目
山东省自然科学基金资助项目(Y2008B49). （Y2008B49）
