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介孔生物活性玻璃/脱钙骨复合支架的制备及性能研究

薛士壮 朱海霖 陈建勇 冯新星 常江

无机材料学报2011,Vol.26Issue(10):1068-1072,5.
无机材料学报2011,Vol.26Issue(10):1068-1072,5.DOI:10.3724/SP.J.1077.2011.01068

介孔生物活性玻璃/脱钙骨复合支架的制备及性能研究

Preparation and Properties of Mesoporous Bioactive Glass / Demineralized Bone Composite Scaffolds

薛士壮 1朱海霖 1陈建勇 1冯新星 1常江2

作者信息

  • 1. 浙江理工大学先进纺织材料与制备技术教育部重点实验室,材料与纺织学院,杭州310018
  • 2. 中国科学院上海硅酸盐研究所高性能陶瓷和超微结构国家重点实验室,上海200050
  • 折叠

摘要

Abstract

The composite scaffolds (MBG/DB) were prepared successfully through immersing the mesoporous bioactive glass powders into the demineralized bones. The bovine cancellous bone, demineralized bone, composite scaffold were investigated and characterized by FTIR, SEM, XRD and universal electromechanical testing machine. The results show that the compressive strength of the demineralized bones is about (1.10+0.31)Mpa, the porosity is about 71% and the pore size is in the range from 200 to 600μm. However, the porosity and the compressive strength of the composite scaffolds are decreased to 40% and increase markedly to (8.49 + 2.14)Mpa, respectively. Meanwhile, the composite scaffolds show good bioactivity in vitro.

关键词

介孔生物活性玻璃/脱钙骨/复合支架/生物活性

Key words

mesoporous bioactive glass/ demineralized bone/ composite scaffold/ bioactivity

分类

医药卫生

引用本文复制引用

薛士壮,朱海霖,陈建勇,冯新星,常江..介孔生物活性玻璃/脱钙骨复合支架的制备及性能研究[J].无机材料学报,2011,26(10):1068-1072,5.

基金项目

国家自然科学基金(50973096,50903073,31070867) (50973096,50903073,31070867)

浙江省科技厅公益项目(2010C31038) (2010C31038)

无机材料学报

OA北大核心CSCDCSTPCDSCI

1000-324X

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