摘要
Abstract
Objective To observe the clinical effect of noninvasive ventilation( NIPPV) in treatment with chronic obstructive pulmonary disease(COPD) with respiratory failure. Methods From December 2009 to December 2010, 102 cases with COPD complicated respiratory failure were randomly classified into two groups, which control group with 51 cases were treated with normal therapy and treatment group with 51 cases were treated with NIPPV at the basis of normal therapy. The changes of respiration, heart rate, PaO2 and PaCO2 between the two groups were compared. Results Compared with pretreatment, the respiration and heart rate were not significantly changed(P＞. 05) , PaO2 was significantly increased(P＜0. 05) and PaCO3 was significantly decreased(P＜0. 05)in control group; the respiration, heart rate and PaCO2 were significantly decreased(P＜0. 05) and PaO2 was significantly increased(P＜0. 05) in observation group(P＜0. 05). Moreover, after treatment, the respiration, heart rate, PaO2 and PaCO2 in observation group were significantly better than those in control group(P＜0. 05). The cannula rate in observation group was significantly lower than that in control group(P<0. 05). The hospitalized time of observation group was shorter than control group(P＜0. 05). There was no significant difference in ase-fatality rate between the two groups(P＞0. 05). Conclusion NIPPV in treatment with COPD with respiratory failure can improve respiration, heart rate, PaO2 and PaCO2, degrade cannula rate, shorten hospitalized time, which is a safe and effective method.关键词
慢性阻塞性肺疾病/呼吸衰竭/无创通气Key words
chronic obstructive pulmonary disease/ respiratory failure/ noninvasive ventilation分类
医药卫生
