实用妇产科杂志2011，Vol.27Issue(11)：830-834,5.
无精子症配偶宫颈炎状况及其对宫颈黏液影响的临床研究
Status of Cervicitis and Its Effect on Cervical Mucus in Azoospermic Men's Wives
摘要
Abstract
Objective:To investigate the status of cecviolis and its effect on cervical mucus in azoospermic men's wives. Methods;During June 2010 to October2010, 500 Azoospermic men's wives who were treated in Infertility Clinic of Guangdong Provincial Family Planning Research Institute were recruited and examined for the pathogen and leukocyte from cervical secretions and vaginal discharge. Serum antisperm antibodies (AsAb) , herpes simple virus (HSV) and cytomegalovirus (CMV) were examined by ELISA , meanwhile cervical mucus score < CMS) was recorded during periovulatory phase. Kremers test and sperm-cervical mucus contact (SCMC) test were checked in women with high AsAb level. Results: According to the diagnostic creteria, 500 women were divided into two groups: cervicitis group (n = 92, 18. 4%) and the control group (n=408, 81.6%). The positive rates of chlamydiatrachomatis(CT), ureaplasma urealyticum (UU), bacterial vaginosisi Bvland HPV in cervical mucus in cervicitis group were significantly higher than those in the control group (P <0. 01). Serum HSV and CMV positive rates in cervicitis group were also higher than those in control group( P < 0. 05). The cervical mucus score in cervicitis group was significantly higher than that in the control group (9. 32 ±1. 91 vs. 12. 67 ±2.14, P<0. 05). There were no significant differences in cervical mucus volume, elasticity and fern crystals between the two group( P>0. 05), while there were significant differences in cervical mucus viscosity and cell quantity between the two group (P < 0. 01). The positive rate of serum AsAb level in the cervicitis group was significantly higher than that in the control group (33. 7% vs. 9.8%, P<0.01). The abnormal rates of Kremerstest (10.7% vs. 1.2%) and SCMC test (9.8% vs. 1.2%) in the cervicitis group were also significantly higher than those in the control group( P < 0. 01). Conclusions: Cervicitis may result in some changes of physiochemical characteristic of cervical mucus and im-munological dysfunction of cervix, and induce infertility through several aspects such as the effect on the sperm viability, motility, storage and capacitation. It is important to early diagnose and treat cervicitis in reproductive aged women.关键词
宫颈炎/宫颈黏液/不孕Key words
Cervicitis Cervical mucus/Infertile分类
医药卫生引用本文复制引用
冯苗,李素春,刘标英,潘萍,吴穗妹..无精子症配偶宫颈炎状况及其对宫颈黏液影响的临床研究[J].实用妇产科杂志,2011,27(11):830-834,5.基金项目
广东省计划生育与科学技术委员会科研项目(2009204) （2009204）
