农药学学报2011，Vol.13Issue(5)：496-502,7.DOI:10.3969/j.issn.1008-7303.2011.05.10
高效液相色谱-质谱联用法测定白芍药材中23种农药残留
Determination of 23 pesticide residues in Paeoniae radix Alba using high performance liquid chromatography coupled with mass spectrometry
摘要
Abstract
A method of high performance liquid chromatography coupled with mass spectrometry (HPLC-MS) for simultaneous determination of 23 pesticides in traditional Chinese medicine Paeoniae radix Alba was developed. P. Radix was extracted with acetonitrile, and then purified using a preliminary sample treatment step based on primary-secondary amine (PSA) dispersive solid-phase extraction. Limits of quantification (LOQ) were between 0.75 - 12. 17 μg/kg- Recovery between 70% and 120% were obtained for all pesticides at 0. 01 and 0. 1 mg/kg levels, except for polar pesticides such as thiamethoxam and imidacloprid. This method is accurate, reproducible and has good cleanup effect. It could be applied in pesticide residue analysis in P. Radix.关键词
高效液相色谱-质谱联用法/分散固相萃取/白芍/农药/残留Key words
high performance liquid chromatography-mass spectrometry/ dispersive solid-phase extraction/ Paeoniae radix/ pesticide/ residues分类
化学化工引用本文复制引用
刘银,龚婧如,毛秀红,王柯,季申,王书芳..高效液相色谱-质谱联用法测定白芍药材中23种农药残留[J].农药学学报,2011,13(5):496-502,7.基金项目
“重大新药创制”科技重大专项课题(2009ZX09502-024). （2009ZX09502-024）
