安徽农业科学2011，Vol.39Issue(26)：16127-16129,3.
豆类丝核菌次级代谢产物对小鼠围产期毒性的研究
Study on the Toxicity of Secondary Metabolites of Rhizotonia leguminicola on Mice in Perinatal Period
张伟 1金玉荣 1李友昌1
作者信息
- 1. 广西柳州畜牧兽医学校,广西柳州545003
- 折叠
摘要
Abstract
[Objective] The research aimed to provide experimental basis for the safe application of secondary metabolites of Rhizotonia legumini cola on mice in the clinic. [Method] The gravid maternal mice were randomly divided into normal control group,group of adding 56.62 mg/kg secondary metabolites of R. Leguminicola, group of adding 14. 15 mg/kg secondary metabolites of R. Leguminicola and group of adding 3. 54 mg/kg secondary metabolites of R. Leguminicola. The toxicity of secondary metabolites of R. Leguminicola on mice in the perinatal period was studied. [Result]The body weight of maternal mice on the 21st day after pregnancy decreased significantly (P <0.05). F, birth number and 0-day survival rate of maternal mice in every test group had no significant difference with control group (P > 0.05 ) , but the growth index, viscera index,survival time of swimming,development index of reflex and development index of physiology had significant or extremely significant differ ence with control group. [Conclusion]Under these experimental conditions,secondary metabolites of R. Leguminicola had toxicity on mice in the perinatal period.关键词
豆类丝核菌/次级代谢产物:苦马豆素/围产期毒性Key words
Rhizotonia leguminicola/ Secondary metabolites/ Swainsonine/ Toxicity in the perinatal period分类
农业科技引用本文复制引用
张伟,金玉荣,李友昌..豆类丝核菌次级代谢产物对小鼠围产期毒性的研究[J].安徽农业科学,2011,39(26):16127-16129,3.
