重庆医学2012，Vol.41Issue(1)：28-30,3.DOI:10.3969/j.issn.1671-8348.2012.01.010
甲状腺功能亢进伴白细胞减少患者放射性碘治疗早期白细胞变化随访研究
Radioactive iodine treatment of hyperthyroidism in patients with Leukopenia with early follow-up study
摘要
Abstract
Objective To explore radioactive iodine treatment of hyperthyroidism in patients with leukocyte reduction, while tak ing "white rose" drug short-term changes in white blood cells and early effects. Methods In radioactive iodine treatment of hyper thyroidism in patients, through a multi-center clinical follow-up study to find out the early white cellsCl month and 3 months) fol low-up changes in leukocyte between taking "white rose" drug incombination in patients with leukocyte reduction and patients with normal white blood cells. Comparison of leukocyte reduction in patients with normal white blood cells after treatment of early (6 to 1 year) efficacy. Statistical analysis was performed by two-independence t-test, matched t-test and Chi-square test using software SPSS 17. 0. Results The two groups before and after treatment in a month matched t-test white blood cells, low white blood cell group P<0. 05,WBC normal,P<0. 05. Taking "white rose" drug incombination in patients with leukocyte reduction group was in creased, while patients with normal white blood cells group declined,but still normal ; The two groups before and after treatment in three month matched l-test white blood cells,low white blood cell group P<0. 05 , WBC normal, P>0. 05. Taking "white rose" drug incombination in patients with leukocyte reduction group continue to rise, while patients with normal white blood cells group had no significant changes before treatment in White blood cells level. In the followed up for 6 months to 1 year in two groups of pa tients, no significant difference in two groups,P>0. 05. Conclusion For patients with hyperthyroidism is associated with leukocyte reduction,radioactive iodine therapy in combination "white rose"drug can elevated white blood cell level,thereby reducing the inci dence of thyroid crisis,because of the potential infection induced,due to Leukopenia in the early course of treatment a large number of thyroid hormone into the blood, while no significant difference between the two groups of early effect.关键词
甲状腺功能亢进症/碘放射性同位素/白细胞Key words
hyperthyroidism/iodine radioisotopes/leukocytes引用本文复制引用
郭满涛,李亚明,尹雅芙,蒋宁一..甲状腺功能亢进伴白细胞减少患者放射性碘治疗早期白细胞变化随访研究[J].重庆医学,2012,41(1):28-30,3.基金项目
卫生部公益性卫生行业科研专项基金资助项目(200802028). （200802028）
