SDF-1/CXCR4在老年卵巢癌组织中的表达及意义OACSTPCD
Expressions of chemokine SDF-1 and its receptor CXCR4 in epithelial ovarian tumor of elderly patients and its clinical significance
目的 探讨趋化因子SDF-1及其受体CXCR4在老年人卜皮性卵巢癌组织中的表达及意义.方法 应用western blotting方法定量检测43例老年患者卜皮性卵巢癌组织中SDF-1和CXCR4的蛋白表达情况.结果 老年人上皮性卵巢癌组织中SDF-1/CXCR4蛋白表达较卵巢良性肿瘤对照组明显增加.其相对表达量分别为(2.38±0.20)和(3.32±0.26),差异具有统计学意义(P<0.05).结论 SDF-1/CXCR4生物学轴可能在…查看全部>>
Objective To investigate the expressions and clinical significance of chemokine SDF-1 and its receptor CXCR4 in elderly patients with epithelial ovarian tumor. Methods 43 cases with epithelial ovarian cancer were studied ran-domly. The expressions of SDF-1 and CXCR4 proteins were detected by Western blotting. Results There were weak ex-pression of SDF-1 and modest expression of CXCR4 in benign ovarian tumor of elderly patients. The expressions of SDF-1 prote…查看全部>>
李雅丽;辛维政;王轶英
450003,郑州市,河南省人民医院妇产科450003,郑州市,河南省人民医院麻醉科450003,郑州市,河南省人民医院妇产科
医药卫生
老年人基质细胞衍生因子-1(SDF-1)CXC族趋化因子受体4(CXCR4)卵巢癌
Elderly SDF-1 CXCR4 Epithelial ovarian tumor
《老年医学与保健》 2011 (6)
349-350,356,3
河南省医学科技攻关计划(2011020138)
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