老年医学与保健2011，Vol.17Issue(6)：372-374,3.DOI:10.3969/j.issn.1008-8296.2011-06-18
息宁控释片对帕金森病运动并发症的疗效研究
Efficacy of sinemet-CR in treatment of motor complications due to Parkinson's disease
丁萍 1魏文石 1陈韵美1
作者信息
- 1. 200040,上海市,复旦大学附属华东医院神经内科
- 折叠
摘要
Abstract
Objective To investigate the efficacy of sinemet-CR in treatment of motor complications due to parkinson's disease (PD). Methods The self-controlled clinical trial was performed in the present study. 80 patients with idiopathic PD were divided into mild group and moderate group according to time of PD and levodopa treatment. The efficacy of si-nemet-CR was assessed by the Unified Parkinson's Disease Rating Scale (UPDRS) scores, Hoehn-Yahr scores , "on" time, "off time and dyskinesias questionnaire. Results Sinemet-CR had significantly increased the "on" time, reduced the "off time, decreased the UPDRS and Hoehn-Yahr scores. There was no significant difference in the frequency of dys-kinesias. Conclusions Sinemet-CR is effective for mild-moderate PD with motor fluctuations, but it is ineffective for dys-kinesias.关键词
息宁控释片/帕金森病/运动并发症Key words
Sinemet-CR/ Parkinson's disease/ Motor complications分类
医药卫生引用本文复制引用
丁萍,魏文石,陈韵美..息宁控释片对帕金森病运动并发症的疗效研究[J].老年医学与保健,2011,17(6):372-374,3.
