Abstract
To explore clinical pathologic factors effect survival time of pancreatic carcinoma with liver metastasis. Methods 41 patients of pancreatic cancer with liver metastasis were reviewed. The follow factors were selected: age, gender, course of disease, symptom, tumor general view, tumor histotype, pathologic grade, infiltration, lymphatic metastasis, complication, operation, operation method, the position, number and the maximum diameter of liver metastasis,time of liver metastasis appeared, treatment of metastasis, chemotherapy after operation, HBsAg, anti-HBs, HBeAg,anti-Hbe,anti-HBc, CEA, CA-125, CA19-9 and liver function. Univariate analysis with Kaplan-Meier methods and multivariate analysis with Cox regression model were carried out. Results The median survival time of pancreatic cancer with liver metastases patients was 8.0 months. Univariate analysis showed ages,course of diseases,the position of liver metastasis,anti-Hbe,anti-HBc,Dbil,Ibil,Dbil/Tbil,total protein,globlin, A/G were the main prognostic factors. Multi-analysis results showed ages, course of diseases, the position of liver metastasis, anti-Hbe, Dbil, Dbil/Tbil, total protein,globlin,A/G were the main prognostic factors. Conclusion Age,course of disease,the position of liver metastasis, anti-Hbe,Dbil,Dbil/Tbil,total protein,globlin,A/G are the main prognostic factors.关键词
胰腺癌/肝转移/生存/COX比例模型Key words
Pancreatic carcinoma/ Liver metastasis/ Survive/ Cox-scale model分类
医药卫生