中国组织工程研究与临床康复2011，Vol.15Issue(49)：9279-9282,4.DOI:10.3969/j.issn.1673-8225.2011.49.037
骨髓间充质干细胞向内皮细胞的分化和临床应用
Differentiation of bone marrow mesenchymal stem cells into endothelial cells and clinical application
康少平 1姜文静 1李萍1
作者信息
- 1. 河北北方学院检验学院临检教研室,河北省张家口市,075000
- 折叠
摘要
Abstract
BACKGROUND: Studies have preliminarily verified that the bone marrow mesenchymal stem cells (BMSCs) can differentiate into endothelial cells.OBJECTIVE: To review the differentiation of BMSCs into endothelial cells and the progress of clinical research. METHODS: PubMed database was searched for articles published from 2000 to 2011 with the key words of "bone marrow mesenchymal stem cell, endothelial cell, differentiation, tissue engineered. The language was limited in English. Meanwhile, Wanfang database was searched for articles published from 2000 to 2011 with the keywords of "bone marrow mesenchymal stem cell, endothelial cell, differentiation, clinical application" in Chinese.Totally 418 articles were retrieved. Andfinalljr31 articles were included..RESULT SAND CONCLUSION: BMSCs have the potential of self renewal and multiplex differentiation. In certain conditions, they can be induced into endothelial cells. Endothelial cells are the important components of tissue-engineered Hoodvessefc. BMSCs for endothelial construction can promote the regeneration of blood vessels in tissue-engineered organs, provide blood supply and also lay the foundation for the treatment of ischemic diseases in clinic.关键词
内皮细胞/骨髓间充质干细胞/分化/组织工程化/综述文献分类
医药卫生引用本文复制引用
康少平,姜文静,李萍..骨髓间充质干细胞向内皮细胞的分化和临床应用[J].中国组织工程研究与临床康复,2011,15(49):9279-9282,4.
