重庆医学2012，Vol.41Issue(3)：249-251,3.DOI:10.3969/j.issn.1671-8348.2012.03.015
血清多肿瘤标志物胃癌诊断判别方程的建立及其临床意义
The establishment and clinical significance of discriminant equation for diagnosis of gastric cancer according to serum multiple tumor markers
余国行 1卿毅 2顾咸庆 2廖玲 2杨宇馨 2王东2
作者信息
- 1. 北京军区天津疗养院肝胆肿瘤科,天津,300381
- 2. 第三军医大学大坪医院野战外科研究所肿瘤中心,重庆,400042
- 折叠
摘要
Abstract
Objective To establish the discriminant equation for diagnosis of gastric cancer according to serum multiple tumor markers,that were detected by C 12 multiple tumor markers protein chip detection system,and raise the diagnostic accuracy of gas tric cancer. Methods Link the tumor markers detection results and the clinical information of 135 initial treatment patients of gas tric cancer,212 digestive system benign disease patients and 6741 health examinations by retrospective study. To adopt to Fisher discriminatory analysis, the discriminant equation for diagnosis of gastric cancer was estabished by SPSS18. 0, and analyzed the difference of diagnostic accuracy of gastric cancer. Results The discriminant equation for diagnosis of gastric cancer was established successfully. The total diagnostic accuracy was 95.0% (the healthy population control group: 96. 1 % ; gastric cancer group: 43. 7%) ,and it was raised significantly compare to single tumor marker. Conclusion The discriminant equation for diagnosis of gastric cancer can increase the diagnostic accuracy, which is significantly better than the single serum tumor marker, and are helpful in clinic.关键词
胃肿瘤/诊断/多肿瘤标志物Key words
gastric neoplasms/ diagnosis/ multiple tumor marker引用本文复制引用
余国行,卿毅,顾咸庆,廖玲,杨宇馨,王东..血清多肿瘤标志物胃癌诊断判别方程的建立及其临床意义[J].重庆医学,2012,41(3):249-251,3.
