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颅外段颈内动脉重度狭窄或闭塞脑梗死解剖模式及与侧支循环的关系

王汉旻 陈晓丽 叶强 徐丽英 童秋玲 黄海波 黄河 潘东波 金得辛

浙江医学2011,Vol.33Issue(12):1714-1716,1749,4.
浙江医学2011,Vol.33Issue(12):1714-1716,1749,4.

颅外段颈内动脉重度狭窄或闭塞脑梗死解剖模式及与侧支循环的关系

Lesion pattern and collateral circulation in patients with cerebral infarction caused by severe stenosis or occlusion of unilateral extracranial carotid artery

王汉旻 1陈晓丽 1叶强 1徐丽英 1童秋玲 1黄海波 1黄河 1潘东波 2金得辛1

作者信息

  • 1. 325000,温州医学院附属第一医院脑科中心
  • 2. 温州市第八人民医院内科
  • 折叠

摘要

Abstract

To investigate the lesion pattern and collateral blood flow in patients with cerebral infarction causedby severe stenosis or occlusion of unilateral extracranial internal carotid artery (ICA).Forty two patients with acute is-chemic stroke shown on diffusion-weighted imaging (DWI) and stenosis ( ^70%) or an occlusion of unilateral extracranial ICA confirmed by cerebral angiography, including 20 patients with severe stenosis and 22 with occlusion, were enrolled in the study within 3 days of onset. The ischemic lesions and primary collateral pathway were compared between two groups, and the relationship between ischemic lesions and primary collateral pathway was analyzed.ResultsMultiple ischemic lesions in severe stenosis or occlusion of extracranial ICA was 80%, the presence of border-zone infarct (BZI) concomitant partial infarct (PI) was higher in severe stenosis group than that in occlusion group( P<0.01). The presence of collateral flow via anterior communicating artery (ACoA) and posterior communicating artery (PCoA) was higher in occlusion group than that in severe stenosis group (P< 0.05), the prevalence of collateral flow via PcoA was higher in severe stenosis group than that in occlusion group( P<0.05). There was an increased prevalence of external border zone infarcts in the group without ACoA collateral flow compared with the group with ACoA collateral flow (P<0.05). No differences were found for any other ischemic lesions and collateral pathway. An acute ischemic lesion in ICA severe stenosis or occlusive disease is mainly multiple. Collateral flow via the ACoA is associated with a reduction of the prevalence external border zone lesions, but not with any other type of ischemic lesion.

关键词

颈内动脉/梗死/动脉粥样硬化/侧支循环

Key words

Internal carotid artery/ Infarction / Atherosclerosis/ Collateral circulation

引用本文复制引用

王汉旻 ,陈晓丽,叶强,徐丽英,童秋玲,黄海波,黄河,潘东波,金得辛..颅外段颈内动脉重度狭窄或闭塞脑梗死解剖模式及与侧支循环的关系[J].浙江医学,2011,33(12):1714-1716,1749,4.

基金项目

温州市科技计划项目(Y20060266、Y20100149) (Y20060266、Y20100149)

温州市鹿城区科技局科技文化项目(S090208) (S090208)

浙江医学

OACSTPCD

1006-2785

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