中国组织工程研究与临床康复2011，Vol.15Issue(53)：9981-9985,5.DOI:10.3969/j.issn.1673-8225.2011.53.025
彩色多普勒超声评价肾缺血再灌注后模型兔肾动脉血流动力学变化及与肾功能的关系
Correlation between renal arterial hemodynamic alterations and renal functions evaluated by color Doppler ultrasound using a rabbit renal ischemia reperfusion model
摘要
Abstract
BACKGROUND: Previous diagnose of renal ischemia reperfusion mainr/ depends on biochemical and pathological examination.Color Doppler flow imaging (CDFI) can mini-invasn/ely rapidly display renal blood flow changes following renalischemia/reperfusion injury.OBJECT P/E: To evaluate rabbit renal arterial hemodynamical changes after renal ischemia reperfusion using CDFI. and aruryz*the correlation between arterial hemodynamical changes and renal function indices including blood urea nitrogen (BUN) andcreatinine(Cre).METHODS: Fifty-six r abb rts were randomly divided into normal control group, ischemia reperfusion group and sham operationgroup. Rabbrts were established into renal ischemia reperfusion model: in the ischemia reperfusion group. Rabbits in the shamoperation group underwent resection of the right kidney. No treatment was performed in the control group. According to differenttime points, three subgroups were used in the former two groups.RESULT SAND CONCLUSION: With aggravation of renal ischemia reperfusion injury, the systolic velocity, pulsatilrty index.resistance index and BUN and C re were gradual^ increased and reached the peak at24 hours. Hemodynamical changes firstappeared in the interlobar artery. Resistance index is the most sensrtn/e index to reflect the degree of renal ischemia reperfusioninjury. CDFI is an effective method to evaluate renal ischemia/reperfusion injury degree.关键词
彩色多普勒超声/肾缺血再灌注/血流动力学/肾功能/功能指标分类
医药卫生引用本文复制引用
宣吉晴,彭莉晴,李明星,李昆萍,罗志建..彩色多普勒超声评价肾缺血再灌注后模型兔肾动脉血流动力学变化及与肾功能的关系[J].中国组织工程研究与临床康复,2011,15(53):9981-9985,5.基金项目
四川省卫生厅资助课题(070243),彩色与能量多普勒显像定量评价肾缺血再灌注组织炎症反应的实验研究. （070243）
