中国组织工程研究与临床康复2011，Vol.15Issue(49)：9271-9274,4.DOI:10.3969/j.issn.1673-8225.2011.49.035
骨髓间充质干细胞在组织工程研究中的应用进展
Application progress of bone marrow mesenchymal stem cells in tissue-engineering research
摘要
Abstract
BACKGROUND: Bone marrow mesenchymal stem cells (BMSCs) play a significant role in tissue engineering as good seedcells.OBJECTIVE: To descriptthe experimental status of BMSCs in the bone, cartilage, liver, tendons and hearttissue engineeringapplications, clarify the momentous ness role of BMSCs in tissue engineering.METHODS: A computer-based online search was conducted in NCBI database and PubMed database for literatures about theapplication of BMSCs in tissue engineering published from January 2000 to October 2010 with the key words cf'Bone msirowmesenchymal stem cells. Mesenchymal stem cells, tissue engineering" in English. Exclusive criteria included repetitive studiesand no original research.RESULT SAND CONCLUSION: According to the included and excluded criterion, a total of 33 references were selected toanalysis. BMSCs proliferation activity, had potentiality of multi-directional differentiation, it couId differentiated to osteo blasts,chondrocytes, hepatocytes, tendon cells and myocardial cells. Therefore, BMSCs might be favorable seed cell to utilize htissueengineering, and treated clinical correlated diseases. This article confirmed BMSCs had a highly utilization value in tissueengineering, and was hoped to solve puzzlers problems applied with tissue engineering in the treatment of related diseases.关键词
骨髓间充质干细胞/组织工程/分化/应用进展/综述文献分类
医药卫生引用本文复制引用
赵大成,汪玉良,党跃修,赵琳..骨髓间充质干细胞在组织工程研究中的应用进展[J].中国组织工程研究与临床康复,2011,15(49):9271-9274,4.基金项目
甘肃省自然科学研究基金(2009GS02583). （2009GS02583）
