广西医学2012，Vol.34Issue(1)：16-20,5.
超声、钼钯、MRI对乳腺癌诊断价值的Meta分析
Value of Ultrasonography,Mammography and Magnetic Resonance Imaging in Diagnosis of Breast Cancer:A Meta-analysis
摘要
Abstract
Objective To compare the value of ultrasonography( US ),mammography( MAM )and magnetic resonance imaging(MRI )in the diagnosis of breast cancer with Meta-analysis. Methods Articles reporting US,MAM and MRI data of patients with known or suspected breast cancers were searched in the Cochrane Library, MEDL EVE, EMBASE, CBM, CNKI, VIP. Study quality was assessed and data extraction was performed. Statistic analysis was performed with Meta-disc 1.4 software. Results Nine articles involving 1370 lesions were included in this Meta-analysis. Significant heterogeneity was present except the sensitivity of US and MRI in these studies. The fixed effect model and random effect model were both correspondingly used. Sensitivities of US,MAM,MRI were 84% ,75% ,95% and specificities were 70% ,71% and 66% respectively. Area under the curve( AUC )of summary receiver operating chaiacteristic( SROC ) curve were 86.6% ,81.6% ,95.8% respectively. AUC of combined diagnosis using the three methods together was 98.6%. In the Meta-regression analysis,covariate of age was associated with US,as well as BI-RADS with MAM. Conclusion US, MAM and MRI are valuable diagnostic methods for breast cancer,but the combination of these three methods is greatest valuable.关键词
乳腺癌/超声/钼钯/磁共振成像/Meta分析Key words
Breast cancer/ Ultrasonography/ Mammography/ Magnetic resonance imaging/ Meta-analysis分类
医药卫生引用本文复制引用
蒋芳艳,李智贤,田桂湘,黄深..超声、钼钯、MRI对乳腺癌诊断价值的Meta分析[J].广西医学,2012,34(1):16-20,5.基金项目
广西科学研究与技术开发计划资助项目(桂科攻1140003A-9) （桂科攻1140003A-9）
