中国病理生理杂志2012，Vol.28Issue(1)：181-185,5.DOI:10.3969/j.issn.1000-4718.2012.01.036
MicroRNAs与可卡因成瘾关系的研究进展
Advance in the relationship between microRNAs and cocaine addiction
摘要
Abstract
Cocaine addiction involves a variety of complex mechanisms, including neural, transcriptional and signal transductional processes. In recent years, many studies have shown that some microRNAs can weaken the rewards of drug effect and suppress the formation of cocaine addiction. On the other hand, some microRNAs, such as ADICD microR-Nas, contribute to cocaine addiction. Therefore, regulating the transcriptional levels of these microRNAs and the expression of their targeting genes may provide a new approach for the treatment of cocaine addiction. This article reviews the structure and function of microRNAs involved in cocaine addiction and the relationship between microRNAs and cocaine addiction.关键词
微小RNAs/可卡因成瘾/cAMP反应元件结合蛋白质Key words
MicroRNAs/Cocaine addition/cAMP response element -binding protein分类
医药卫生引用本文复制引用
王芬芬,沈杰,张吉翔..MicroRNAs与可卡因成瘾关系的研究进展[J].中国病理生理杂志,2012,28(1):181-185,5.基金项目
国家自然科学基金资助项目 (No.30360037) （No.30360037）
