中国神经再生研究（英文版）2012，Vol.7Issue(1)：31-35,5.DOI:10.3969/j.issn.1673-5374.2012.01.005
Morphological and migratory alterations in retinal Müller cells during early stages of hypoxia and oxidative stress
Morphological and migratory alterations in retinal Müller cells during early stages of hypoxia and oxidative stress
Xiaohui Zhang 1Zhaohui Feng 1Chunhua Li 1Yuping Zheng1
作者信息
- 1. Department of Ophthalmology, Second Affiliated Hospital of Xi'an Jiaotong University Medical College, Xi'an 710004, Shaanxi Province, China
- 折叠
摘要
Abstract
In the present study, retinal Müller cells were cultured in vitro and treated with hydrogen peroxide (oxidative stressor) and cobalt chloride (hypoxic injury). Following 24 hours of culture, compensatory hypertrophy was observed and cellular apoptosis increased. Hypoxia enhanced the migration ability of retinal Müller cells and induced the expression of α-smooth muscle actin. Oxidative stress altered the morphology of Müller cells when compared with hypoxia treatment.关键词
retina/Müller cells/hypoxia/oxidative stress/migration/glutamine synthetase/α-smooth muscle actin/neural regenerationKey words
retina/Müller cells/hypoxia/oxidative stress/migration/glutamine synthetase/α-smooth muscle actin/neural regeneration引用本文复制引用
Xiaohui Zhang,Zhaohui Feng,Chunhua Li,Yuping Zheng..Morphological and migratory alterations in retinal Müller cells during early stages of hypoxia and oxidative stress[J].中国神经再生研究（英文版）,2012,7(1):31-35,5.
