畜牧兽医学报2011，Vol.42Issue(1)：8-17,10.
系统发育谱法研究牛蛋白质相互作用网络
The Study of Protein Interaction Network of Cattle Based on the Phylogenetic Profile
摘要
Abstract
The objective of this study was to study the protein interaction network of cattle based on the phylogenetic profile and to provide useful information for the post-genome program of cattle, and the results could be used in production of cattle. The known protein-protein interaction (PPI) data set of C. Eiegans, S. Cerevisiae and Homo sapien were used to deduce the PPI of cattle based on phylogenetic profile in this paper. A PPI network of cattle which included 2 953 proteins and 3 034 interactions was obtained. The analysis of PPI network showed that it was a scale-free property network and 23 unknown proteins including ENSBTAP00000011562 were annotated. The results showed that the partial network related to proteins of lipid metabolism was analyzed based on the known protein information. The result provide effective information for improving the quality and production of milk.关键词
牛/蛋白相互作用/相互作用网络/功能预测/脂代谢Key words
cattle/protein interaction/interaction network/function prediction/lipid metabolism分类
畜牧业引用本文复制引用
沈庆航,徐加豹,江明锋,钟金城..系统发育谱法研究牛蛋白质相互作用网络[J].畜牧兽医学报,2011,42(1):8-17,10.基金项目
四川省青年科技基金(09ZQ026-011) （09ZQ026-011）
