疑难病杂志2012，Vol.11Issue(2)：88-90,3.DOI:10.3969/j.issn.1671-6450.2012.02.004
半胱氨酸蛋白酶抑制剂C与冠心病的相关性研究
Correlation between serum cystatin C and coronary artery disease
摘要
Abstract
Objective To investigate the relationship between serum cystatin C( Cys C ) concentrations and coronary artery disease ( CAD ) with different severity. Methods All the patients were divided into three groups: stable angina pectoris ( SAP, n = 60 ) group, acute myocardial infarction ( AMI, n = 52 ) group and healthy control group( n =40 ). Serum Cys C concentration was measured by ELISA assay, and the left ventricular ejection fraction ( LVEF ) was measured too. These parameters were analyzed at the same time. Results The concentration of serum Cys C in SAP group was higher than that in healthy control group( P <0.05 ), and there was negative correlation with LVEF( r = -0.218, P <0.05 ). The concentration of serum Cys C in AMI group was lower than that in healthy control group( P <0. 05 ), and there was positive correlation with LVEF( r = 0. 347, P < 0. 01 ). Conclusion There was close relationship between Cys C and development of coronary artery disease. Severity of coronary artery disease and heart function can be reflected by Cys C indirectly.关键词
半胱氨酸蛋白酶抑制剂C/冠心病/相关性Key words
Cystatin C/ Coronary artery disease/ Correlation引用本文复制引用
陈丹,蒋学俊,文英,任珊..半胱氨酸蛋白酶抑制剂C与冠心病的相关性研究[J].疑难病杂志,2012,11(2):88-90,3.
