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声脉冲辐射力成像技术评价慢性乙型肝炎肝纤维化程度的研究

张纯林 朱先存 罗福成 左鲁生 童清平

实用肝脏病杂志2012,Vol.15Issue(1):4-6,3.
实用肝脏病杂志2012,Vol.15Issue(1):4-6,3.DOI:10.3969/j.issn.1672-5069.2012.01.002

声脉冲辐射力成像技术评价慢性乙型肝炎肝纤维化程度的研究

Acoustic radiation force impulse in evaluation of liver fibrosis in patients with chronic hepatitis B

张纯林 1朱先存 2罗福成 1左鲁生 2童清平1

作者信息

  • 1. 230031,合肥市,安徽医科大学解放军临床学院/第105医院超声科
  • 2. 蚌埠市解放军第123医院超声科
  • 折叠

摘要

Abstract

Objective To analyse the application value of acoustic radiation force impulse in diagnozing liver fibrosis.Method The right lobes of the liver in 52 patients with chronic hepatitis B and 31 healthy subjects were checked by acoustic radiation force impulse imaging technology in order to measure quantitative value of liver tissue elasticity in regions of interest. Result The virtual touch quantification (VTQ) values in patients with chronic hepatitis B were higher than that in healthy control (P=0.012) ; The VTQ value was positively correlated to the degrees of liver fibrosis (Spearman r=0.737,P<0.01) ;The liver biopsy results of ≥G3S3 were considered as middle/high-staging liver fibrosis;The VTQ value of 1.6m/s was used as cut-off value and its sensitivity was 93. 8%; the specificity was 73.7%and the accuracy was 85.1% to diagnose middle/high-staging liver fibrosis. Conclusion Acoustic radiation force impulse imaging technology might reflect quantitative information of the liver tissue elasticity , which can be used to assess the degree of liver fibrosis.

关键词

慢性乙型肝炎/肝纤维化/声脉冲辐射力成像/声触诊组织量化/诊断

Key words

Hepatitis B/Liver fibrosis/ Acoustic radiation force impulse/ Virtual touch quantification/Diagnosis

引用本文复制引用

张纯林,朱先存,罗福成,左鲁生,童清平..声脉冲辐射力成像技术评价慢性乙型肝炎肝纤维化程度的研究[J].实用肝脏病杂志,2012,15(1):4-6,3.

实用肝脏病杂志

OACSTPCD

1672-5069

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