实用医学杂志2012，Vol.28Issue(1)：74-76,3.DOI:10.3969/j.issn.1006-5725.2012.01.032
高血压病患者心脏结构及功能变化与心房颤动关系的研究
Relationship between the changes of heart structure and function and atrial fibrillation in patients with essential hypertension
林文辉 1邵健智 1王齐增 1李新祥 1朱玲军 1林斌 1马湘俊 1周仁芳1
作者信息
摘要
Abstract
Objective To investigate the changes of heart structure and function in patients with essential hypertensive (EH) complicated with atrial fibrillation (AF). Methods All 125 patients with EH were recruited which included EH without AF (Group A,n = 75), EH with paroxysmal AF (Group B,n = 30) , EH with persistent or permanent AF (Group C,n = 20). The arrhythmias were monitored by 24-houre ambulatory electrocardiogram, while the heart structure and function were evaluated by Doppler-chocardiography. Plasma level of B-type natriuretic peptide (BNP) was measured by a point-of-care immunoassy. Results The left atrial diameters (LAD), interventricular septal thickness (IVST), left ventricular posterior wall thickness (LVPWT), left ventricular end systolic diameters (LVESd) , left ventricular end diastolic diameters (LVEDd) , left ventricular mass index (LVMI), relative left wall thickness (RWT), and plasma level of BNP in Group C were the highest, and the left ventricular ejection fraction (LVEF) was the lowest, and were significantly different from those in Group A and B (P < 0.05). The LAD , LVMI, and plasma level of BNP in Group B were greater than those in Group A (P < 0.05). Conclusion Heart structure and function were changed in patients with EH complicated with AF, especially in those complicated with persistent or permanent AF.关键词
高血压/心房颤动/心脏重构/心脏功能/B型钠尿肽Key words
Hypertension/Atrial fibrillation/Cardiac remodeling, heart function/B-type natriuretic peptide引用本文复制引用
林文辉,邵健智,王齐增,李新祥,朱玲军,林斌,马湘俊,周仁芳..高血压病患者心脏结构及功能变化与心房颤动关系的研究[J].实用医学杂志,2012,28(1):74-76,3.
