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四味藏木香软胶囊对环磷酰胺致小鼠免疫低下模型的影响

陈湘宏 童丽 王津慧 翁裕馨 刘燕

安徽农业科学2011,Vol.39Issue(30):18556-18557,18560,3.
安徽农业科学2011,Vol.39Issue(30):18556-18557,18560,3.

四味藏木香软胶囊对环磷酰胺致小鼠免疫低下模型的影响

Effects of Four Tastes Inulahelenium I Soft Capsule on the Low-immunity Model of Mice Caused by Cyclophosphamide

陈湘宏 1童丽 1王津慧 1翁裕馨 1刘燕1

作者信息

  • 1. 青海大学医学院,青海西宁810001
  • 折叠

摘要

Abstract

[objective] The aim was to study on the effects of four tastes Inula helenium I soft capsule on the low - immunity model of mice caused by cyclophosphamide. [Method] Taking mice in Running as the animal model,mice were divided into blank group,model group,positive medicine group (levamisole hydrochloride tablets) ,and four tastes Inula helenium I soft capsule group (high and low doses). The phagocytic rate and phagocytic index of peritoneal macrophages in mice low - immunity model caused by cyclophosphamide were observed. Effects of the mice he-molysin antibody formation and drugs on the mice delayed hypersensitivity caused by DNFB were analyzed by the hemolysin antibody mensuration. [Result] Compared with the model group,four tastes Inula helenium I soft capsule could significantly enhance the phagocytic rate and phagocytic index of peritoneal macrophages in mice,and promote the hemolysin antibody formation in mice. In the test,the mice with delayed hypersensitivity showed significant differences in the left and right ear weight. It was also higher than the model group and blank group, indicating significant differences and having statistical significance. [ Conclusion] Four tastes Inula helenium I soft capsule could enhance the immune function of mice caused by cydophosphamide.

关键词

四味藏木香软胶囊/环磷酰胺/小鼠免疫抑制模型

Key words

Four tastes Inula helenium I soft capsule/ Cyclophosphamide/ Mice low - immunity model

分类

农业科技

引用本文复制引用

陈湘宏,童丽,王津慧,翁裕馨,刘燕..四味藏木香软胶囊对环磷酰胺致小鼠免疫低下模型的影响[J].安徽农业科学,2011,39(30):18556-18557,18560,3.

基金项目

青海省科技厅项目(2010-Z-714). (2010-Z-714)

安徽农业科学

0517-6611

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