安徽农业科学2011，Vol.39Issue(30)：18603-18604,2.
2-(4-甲氧基苯基)苯并咪唑的合成
The Synthesis of 2-(4-methoxyphenyl) Benzimidazole
摘要
Abstract
[Objective] The para-chlorobenzaldehyde and o-phenylene diamine were directly synthesized into 2-(4-methoxyphenyl) benzimidazole in phosphoric acid. [Method] The process conditions of 2-(4-methoxyphenyl) benzimidazole synthesis were optimized by single factor experiment. The structure of target product was confirmed by using melting point detector, elementary analyzer and infrared spectrum. [ Result] The ratio between o-phenylene diamine and para-chlorobenzaldehyde was 1.0:1.2; the reaction time was 3 h; the reaction temperature was 44 ℃ ; under above conditions, the yield of 2-(4-methoxyphenyl) benzimidazole may reach 72.8%. In the same conditions, the repeating experiments are also done which offered the average yield of 72.5%. [ Conclusion] The process route has some advantages of good-color product, simple operation and less corrosive, so it will have good application value.关键词
苯并咪唑/对甲氧基苯甲醛/邻苯二胺/合成Key words
Benzimidazole/ Para-chlorobenzaldehyde/ O-phenylene diamine/ Synthesis分类
农业科技引用本文复制引用
罗亚楠,于丽颖,刘立群..2-(4-甲氧基苯基)苯并咪唑的合成[J].安徽农业科学,2011,39(30):18603-18604,2.基金项目
吉林省教育厅科研项目(2010N0176). （2010N0176）
