法医学杂志2011，Vol.27Issue(5)：334-336,3.DOI:10.3969/j.issn.1004-5619.2011.05.005
三联体亲权指数的统一算法及其扩展应用
Universal Algorithms for Paternity Index in Trios and Its Extended Application
摘要
Abstract
Objective To introduce an universal algorithm for kinship index between a baby and a random person with biologic mother reference. Methods Based on the formulas of paternity index in trios (PIT), common factors shared in these formulas were deduced following reconstructions of these formulas with the common factors. Universal algorithms for other common kinship indices, such as grandparental index (GI), half sibling index (HIS), avuncular index (AI) and first cousin index (CI1st), were investigated according to avuncular index rule and the coefficient of relationship (r). Results The common factor shared in the formulas for PIT calculation was 1 plus reciprocal of the frequency of the allele with identity by state between the alleged father and the detected baby. Two general formulas for PIT, GI, AI, HIS and CI1st, with biologic mother reference were successfully established with the common factor and r value. Conclusion The calculation was simplified with the universal algorithms for common kinship indices between random person and the baby with biologic mother reference and the batch arithmetic operation with the universal algorithms can be easily realized with programming.关键词
法医遗传学/亲子关系/算法/亲权指数/三联体Key words
forensic genetics/ parent-child relations/ algorithms/ paternity index/ trios分类
社会科学引用本文复制引用
阙庭志,张素华,赵书民..三联体亲权指数的统一算法及其扩展应用[J].法医学杂志,2011,27(5):334-336,3.基金项目
中央级公益性科研院所基本科研业务费专项资金项目(GY1103) （GY1103）
