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维吾尔族与汉族肾移植术后患者他克莫司全血谷浓度的对比分析

阿不都克依木·扎依提 迪丽达尔·克依木 米娜瓦尔·哈帕尔

中国临床药学杂志2011,Vol.20Issue(6):336-339,4.
中国临床药学杂志2011,Vol.20Issue(6):336-339,4.

维吾尔族与汉族肾移植术后患者他克莫司全血谷浓度的对比分析

Comparative analysis of whole blood tacrohmus concentrations between Uygur and Han patients after renal transplantation

阿不都克依木·扎依提 1迪丽达尔·克依木 1米娜瓦尔·哈帕尔1

作者信息

  • 1. 新疆医科大学第一附属医院药学部,乌鲁木齐830054
  • 折叠

摘要

Abstract

AIM To compare difference of whole blood tacrohmus concentrations between Uygur and Han patients at different stages after renal transplantation, and to provide basis for individualized tacrohmus therapy. METHODS The whole blood tacrohmus concentrations in 1 142 samples from 21 Uygur and 25 Han patients were measured using Emit 2000 assay method. The patients were grouped according to the ethnicity and post surgical time course, and the results were analyzed by statistics. RESULTS The whole blood tacrohmus concentrations of Uygur and Han patients at varies time course of < 1 month, 1-3 months,4-6 months,7-12 months, > 12 months were (13.49 ± 4.16), (11.75±3.87),(8.09±2.19), (7.17 ±3.41), (5.74 ±2.93) μg·L-1,and (11.95 ± 3.32), (10.66 ± 3.33), (8.09±2.19),(6.31±2.43) and (4.91 ± 2.15) μg·L-1, respectively. There were significant differences of wholeblood tacrohmus concentrations between Uygur and Han patients ( P < 0.05). CONCLUSION After renal transplantation, whole blood tacrohmus concentrations of Uygur patients are higher then Han patients.

关键词

维吾尔族/汉族/肾移植/他克莫司全血谷浓度/对比分析

Key words

Uygur/ Han/ renal transplantation/ whole blood tacrohmus concentration/ comparitive analysis

引用本文复制引用

阿不都克依木·扎依提,迪丽达尔·克依木,米娜瓦尔·哈帕尔..维吾尔族与汉族肾移植术后患者他克莫司全血谷浓度的对比分析[J].中国临床药学杂志,2011,20(6):336-339,4.

中国临床药学杂志

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