摘要
Abstract
Objective To study the changes in hemodynamics, concentrations of epinephrine (E) and angiotensin (AT Ⅱ ) in plasma when the SLIPATM laryngeal mask or tracheal tube was inserted at different depths of anesthesia for the purpose of analyzing the optimum anesthesia depth for the SLIP ATM laryngeal mask and its effects on stress responses . Methods 120 patients were divided into six groups according to the airway management and bispectral index(BIS) ,I. E. Al , A2, A3, Bl , B2 and B3. The SLIPATM laryngeal mask or tracheal tube was inserted respectively, when BIS was 40,50 and 60. Hemodynamics ( MAP, HR) and blood samples for adrenaline and angiotensin Ⅱ were collected at different time points, I. E. Base, insertion, 1 ,3 and 5 min after insertion(TO,TI , T2,T3,T4). Results (1)Changes in hemodynamics: MAP in groups Aland Bl at T1 decreased in comparison with TO. Compared with T1, MAP and HR in each group increased from T2 except group Al ( P < 0. 05 ). Moreover, MAP in group B3 was significantly higher than that in group A3 at T2, T3 and T4 (P < 0. 05). (2) Changes in the stress level, compared with T1 , adrenaline concentration in group A3 and B2 increased from T2 ( P < 0. 05) , but angiotensin Ⅱ concentration from T3. Furthermore, both adrenaline and angiotensin Ⅱ in group B3 increased from T2 to T4 ( P < 0. 05 or P < 0. 01). Angiotensin Ⅱ at T2, T3 T4 were higher in group B3 than those in group A3 (P < 0. 05). Conclusions BIS 50 is an appropriate depth of anesthesia for SLIPATM laryngeal mask insertion, with few effects on stress responses, compared with endotracheal intubation.关键词
SLIPATM喉罩/气管内插管/应激/麻醉深度Key words
SLIPATM laryngeal mask/ endotracheal intubation/ stress responses/ depth of anesthesia分类
医药卫生
