安徽农业科学2011，Vol.39Issue(23)：14180-14182,3.
Al3+对蚯蚓和家兔乙酰胆碱酯酶的毒性研究
Toxicity of Aluminum on Acetylcholinesterase(AChE) of Earthworm and Habit
摘要
Abstract
[Objective] The aim was to study the toxicity of aluminum on acetylcholinesterase( AChE) of earthworm and habit. [ Method] The toxicity of aluminum on AChE of habit brain and earthworm were evaluated in vitro. [ Result ] AChE activities were depressed significantly by concentration ranges of Al3+. The IC50 values of Al3+ on AChE activity of earthworm and habit brain were 5.4 and 4. 2 mmol/L, respectively.The bimolecular rate constant (Ki) of 4.2 mmol/L Al3+ on AChE of habit brain was 1.02 times more than that of 5.4 mmol/L Al3+ on AChE of earthworm, which suggested that AChE from habit brain has higher sensitivity to Al3+ than that of earthworm. [Conclusion] The research provides theoretical basis for clarifying the toxicity of aluminum on AchE from the whole of animal life layer and fastly determining the pollution of aluminum by AchE.关键词
乙酰胆碱酯酶/AJ3+/毒性Key words
Acetylcholinesterase/Aluminum/Toxicity分类
农业科技引用本文复制引用
张轶辉,王波,崔小伟,毕亚玲..Al3+对蚯蚓和家兔乙酰胆碱酯酶的毒性研究[J].安徽农业科学,2011,39(23):14180-14182,3.基金项目
安徽科技学院引进人才项目(zrc2008203). （zrc2008203）
