西安交通大学学报（医学版）2011，Vol.32Issue(5)：589-591,609,4.
一种新的鸡胚尿囊膜模型的建立与应用
Construction and application of a new model of chicken chorioallantoic membrane
摘要
Abstract
Objective To construct a new model of chicken chorioallantoic membrane (CAM) and investigate the inhibition of hydrocortisone on CAM angiogenesis. Methods The CAM was constructed by air chamber. The carriers of silastic ring, methylcellulose, gelatin sponge and fiberglass filter paper were used. Results The new CAM model was ideal for anti-angiogenesis drug screening. The carrier of silastic ring had the property of direct-viewing, accurate application of sample, and convenient observation. Hydrocortisone had a good inhibitory effect on angiogenesis of CAM in the dose-effect manner. Conclusion The new CAM model is a tool for angiogenesis research. Hydrocortisone has an obvious inhibitory effect on angiogenesis of CAM by CAM model.关键词
血管生成/鸡胚尿囊膜/抑制剂/氢化可的松Key words
angiogenesis/chicken chorioallantoic membrane/inhibitor/hydrocortisone分类
医药卫生引用本文复制引用
张彦民,王红英..一种新的鸡胚尿囊膜模型的建立与应用[J].西安交通大学学报（医学版）,2011,32(5):589-591,609,4.基金项目
国家自然科学基金青年项目(No.81001447)及陕西省自然科学基金资助项目(No.2010JQ4017) （No.81001447）
