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急诊科分离的万古霉素耐药肠球菌的耐药性与同源性研究

熊辉 郑波 王珊

中国临床药理学杂志2011,Vol.27Issue(11):819-821,839,4.
中国临床药理学杂志2011,Vol.27Issue(11):819-821,839,4.

急诊科分离的万古霉素耐药肠球菌的耐药性与同源性研究

Study on the resistance and homology of vancomycin resistant Enterococci from an emergency room

熊辉 1郑波 2王珊2

作者信息

  • 1. 北京大学第一医院急诊科,北京 100034
  • 2. 北京大学第一医院临床药理研究所,北京 100034
  • 折叠

摘要

Abstract

Objective To study the antimicrobial resistance and homolo-gy of vancomycin resistant Enterococci ( VRE) isolated from emergency room. Methods VRE was isolated from patients in an emergency room between November 2005 and December 2008. Minimal inhibition concentrations (MICs) were determined by the two - fold agar dilution method and the van genes were detected by multiplex PCR. Chromosome DNAs were digested by Sma -1 and analysed by PFGE. Results VanA gene of eight E. Faecium isolates from 7 patients were positive. The PFGE profiles demonstrated that the 8 isolates were largely heterogeneous in nature. Conclusion All of the VRE isolate from the emergency room were vanA type E. Faecium. Colonal dissemination was not found in the emergency room.

关键词

肠球菌/万古霉素耐药/急诊科

Key words

Enterococci/ vancomycin resistant/ emergency room

分类

医药卫生

引用本文复制引用

熊辉,郑波,王珊..急诊科分离的万古霉素耐药肠球菌的耐药性与同源性研究[J].中国临床药理学杂志,2011,27(11):819-821,839,4.

中国临床药理学杂志

OA北大核心CSCDCSTPCD

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