国际医药卫生导报2011，Vol.17Issue(23)：2870-2872,3.DOI:10.3760/cma.j.issn.1007-1245.2011.23.010
血液透析联合血液灌流治疗尿毒症皮肤瘙痒疗效观察
Observed the curative effect of treating uremia skin-itch with hemodialysis and hemoperfuison
向远湘 1李勇飞 1米艳梅1
作者信息
- 1. 511800 广东省清新县人民医院肾内科
- 折叠
摘要
Abstract
Objective To explore the curative effect of treating uremia skin-itch with hemodialysis and hemoperfuison.Methods Chose 55 uremia patients taking persistent hemodialysis and having skin-itch; ramdomly divided them into hemodialysis group and hemodialysis combined with hemoperfusion group.25 patients of the hemodialysis group took hemodialysis 2 to 3 times per week.Basing on the treatment of the hemodialysis group,the hemodialysis combined with hemoperfusion group took hemoperfusion every other week.Both groups were treated for 3 months.Observed all patients' skin-itch meliortion.Tested the change of parathyroid hormone,β 2 microglobulin,P,and Ca2+ in blood.Results The patients of hemodialysis combined with hemoperfusion group had lower parathyroid hormone[( 314.5± 182.4) ng/L vs.479.2 ± 207.1ng/L],β 2microglobulin[( 16.1 ± 7.3) mg/Lvs.(24.2 ± 11.2) mg/L],and P3- [( 2.03 ± 0.91 )mmol/L vs.( 2.81 ± 1.42 )mmol/L )]in blood than the patients of hemodialysis group ( P ＜ 0.05 ) and that before treatment ( P ＜ 0.05 ),and got some obvious improvement on skin-itch ( 24/30 ).No patients in hemodialysis group got obvious improvement on skin-itch.Blood parathyroid hormone,β 2 microglobulin,and p3- had no obvious change in the patients of hemodialysis group( P＞0.05 ).Patients' blood Ca2+ in both groups had no obvious change( P＞ 0.05 ).Conclusion Hemodialysis combined with hemoperfusion is an effective treatment method for the uremia patients taking persistent dialysis and having skin-itch.关键词
血液透析/血液灌流/尿毒症/皮肤瘙痒Key words
Hemodialysis/Hemoperfusion/Uremia/Skin-itch引用本文复制引用
向远湘,李勇飞,米艳梅..血液透析联合血液灌流治疗尿毒症皮肤瘙痒疗效观察[J].国际医药卫生导报,2011,17(23):2870-2872,3.
