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生长抑素对大鼠乳腺斯钙素基因表达的影响

汪新建 李惠 李和平 刘凤娟 查光明 郭豫杰 王月影

江西农业学报2011,Vol.23Issue(10):14-16,3.
江西农业学报2011,Vol.23Issue(10):14-16,3.

生长抑素对大鼠乳腺斯钙素基因表达的影响

Effects of Somatostatin on Expression of Stanniocalcin Gene in Mammary Gland of Rat

汪新建 1李惠 2李和平 3刘凤娟 1查光明 1郭豫杰 1王月影1

作者信息

  • 1. 河南农业大学农业部动物生长发育调控重点开放实验室,河南郑州450002
  • 2. 河南农业大学农业部动物生长发育调控重点开放实验室,河南郑州450002
  • 3. 河南省开封市医学科学研究所,河南开封475000
  • 折叠

摘要

Abstract

To investigate the effect of somatostatin on the expression of stanniocalcin gene in the mammary gland of rat, the lacta-ting rats were divided into the control group, CS group and SS group, and the stanniocalcin gene in rat mammary gland was detected by using RT - PCR method. The results indicated that STC1 was expressed in the mammary gland, but there was no STC2 expression. Somatostatin down - regulated the expression of stanniocalcin gene in the mammary gland of the lactating rats, while cysteamine up - regulated the expression of stanniocalcin gene. The above results suggest that somatostatin and cysteamine may be involved in the regulation of calcium metabolism in the mammary gland and play an important role by STC1.

关键词

生长抑素/斯钙素/大鼠/乳腺

Key words

Somatostatin/Stanniocacin/Rat/Mammary gland

分类

生物科学

引用本文复制引用

汪新建,李惠,李和平,刘凤娟,查光明,郭豫杰,王月影..生长抑素对大鼠乳腺斯钙素基因表达的影响[J].江西农业学报,2011,23(10):14-16,3.

基金项目

“十一五”国家科技攻关计划子课题(2006BAD04A03-10) (2006BAD04A03-10)

河南省科技攻关项目(072102140002). (072102140002)

江西农业学报

OACSTPCD

1001-8581

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