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结直肠癌肿瘤相关性贫血相关因素综合分析

葛军娜 于健春 康维明 马志强 古应超

中国医学科学院学报2011,Vol.33Issue(5):549-554,6.
中国医学科学院学报2011,Vol.33Issue(5):549-554,6.DOI:10.3881/j.issn.1000-503X.2011.05.014

结直肠癌肿瘤相关性贫血相关因素综合分析

Comprehensive Analysis of Relevant Factors on Colorectal Cancer-related Anemia

葛军娜 1于健春 1康维明 1马志强 1古应超1

作者信息

  • 1. 中国医学科学院 北京协和医学院 北京协和医院基本外科,北京100730
  • 折叠

摘要

Abstract

Objective To analyze the risk factors of colorectal cancer-related anemia. Method The clinical data of 319 patients with colorectal cancer were retrospectively analyzed for the possible risk factors of tumor-related anemia including tumor location, clinical stage, clinical symptoms, pathology, gender, and age. Results Of these 319 cases, 141 (44.20%) had anemia. The incidence of anemia was 62. 20% among patients with right hemicolon cancers ( including caecum cancer) , and was 23. 82% among patients with rectal cancer and 36. 23% among those with transverse descending or sigmoid colon cancer. Cardia insufficiency, mele-na, tumor location, T staging, hypoproteinemia were also found to be related with anemia. Anemia and hypopro-teinemia were the risk factors for perioperative blood transfusion ( odds ratio = 3. 004, odds ratio = 8. 356, respectively ). Conclusions The colorectal cancer-related anemia is not associated with the clinical stage of the tumor, while cardiac insufficiency, melena, tumor location, tumor stage, and hypoproteinemia constitute the possible risk factors. Anemia and hypoproteinemia are the risk factors of perioperative blood transfusion.

关键词

肿瘤相关性贫血/结直肠癌/低蛋白血症

Key words

tumor related anemia/ colorectal cancer/ hypoproteinemia

分类

医药卫生

引用本文复制引用

葛军娜,于健春,康维明,马志强,古应超..结直肠癌肿瘤相关性贫血相关因素综合分析[J].中国医学科学院学报,2011,33(5):549-554,6.

基金项目

卫生部国家科技支撑计划(2008BAI58B02) (2008BAI58B02)

中国医学科学院学报

OA北大核心CSCDCSTPCDMEDLINE

1000-503X

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