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DAB2IP与肿瘤的发生发展

张天

医学分子生物学杂志2011,Vol.8Issue(6):551-553,3.
医学分子生物学杂志2011,Vol.8Issue(6):551-553,3.DOI:10.3870/j.issn.1672-8009.2011.06.018

DAB2IP与肿瘤的发生发展

DAB2IP and Tumor Development

张天1

作者信息

  • 1. 南方医科大学2007级临床医学八年制,广州市,510515
  • 折叠

摘要

Abstract

Gene DAB2IP ( Disabled homolog 2-interacting protein, DAB2 interacting protein ), also known as AIP1 ( ASK1 -interacting protein 1 ), whose encoded protein is a novel member of Ras GTPase activation protein family. As a tumor suppressor gene, DAB2IP is often downreg-ulated in prostate, breast, lung, liver and other tumors, in relation to promoter methylation and Ezh2. DAB2IP is not only involved in tumor proliferation, survival and apoptosis, but also tumor metastasis.

关键词

DAB2IP/下调/肿瘤转移/前列腺肿瘤

Key words

DAB2IP/ downregulation/ neoplasm metastasis/ prostate neoplasm

分类

医药卫生

引用本文复制引用

张天..DAB2IP与肿瘤的发生发展[J].医学分子生物学杂志,2011,8(6):551-553,3.

医学分子生物学杂志

OACSCDCSTPCD

1672-8009

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