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液态甲醛对雄性小鼠生殖系统的毒性作用研究

张金凤 李慧娟 刘希斌

现代农业科技Issue(22):314-315,2.
现代农业科技Issue(22):314-315,2.

液态甲醛对雄性小鼠生殖系统的毒性作用研究

Toxicity Effects of Liquid Formaldehyde on Reproductive System in Male Mice

张金凤 1李慧娟 1刘希斌2

作者信息

  • 1. 山东建筑大学市政与环境工程学院,山东济南250101
  • 2. 山东城市建设职业学院基础教学部
  • 折叠

摘要

Abstract

To examine the toxicity and abnormality of liquid formaldehyde on reproductive cells in male mice,twenty male Kunming mice were treated with liquid formaldehyde(i.p.)for 7 days,and then testis index,sperm quantities,morphology of sperm,rates of deformation and micronucleus of sperm were investigated.The results indicated that liquid formaldehyde of middle dose group(2.0 mg/kg)and high dose group(20.0 mg/kg)had obvious toxicity on reproductive cells,the testis index and the quantities of sperm clearly decreased,so did the survival and activity rates of sperm.The deformation and micronucleus rates of middle and high dose groups increased obviously compared to the control group.The conclusion was that liquid formaldehyde had obvious toxicity and abnormality on reproduction system in male mice.

关键词

雄性小鼠/液态甲醛/毒性/生殖细胞/微核

Key words

male mice/liquid formaldehyde/toxicity/reproductive cell/micronucleus

分类

医药卫生

引用本文复制引用

张金凤,李慧娟,刘希斌..液态甲醛对雄性小鼠生殖系统的毒性作用研究[J].现代农业科技,2011,(22):314-315,2.

现代农业科技

1007-5739

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