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柴胡对蟾蜍离体心脏功能活动影响的研究

付立波 付艳平 邓红

安徽农业科学2011,Vol.39Issue(35):21829-21830,2.
安徽农业科学2011,Vol.39Issue(35):21829-21830,2.

柴胡对蟾蜍离体心脏功能活动影响的研究

Studies on Effect of RADIX BUPLEURI on the Isolated Heart Function of Toads

付立波 1付艳平 1邓红1

作者信息

  • 1. 长春师范学院生命科学学院,吉林长春130032
  • 折叠

摘要

Abstract

[Objective] To observe the effect of different concentrations of RADIX BUPLEURI decoction on the isolated heart activity of toads. [ Method ] Steinmann' s frog heart perfusion method was used to perfuse different concentrations of RADIX BUPLEURI decoction into the isolated toad heart, and then the cardiac contraction force was recorded by the BL-420E biological function experiment system. [ Result ] 0.009 g/ml decoction had no obvious impact on the toad' s heart contraction amplitude and heart rate (P > 0.05; P > 0.05). However 0.018 g/ml and 0.180 g/ml decoction reduced the heart contraction amplitude and slowed down the heart rate,the effects were all obvious (P <0.01; P <0.01) ,especially 0.180 g/ml decoction,which significantly inhibited the cardiac contraction force and even stopped heart beating. [Conclusion] RADIX BUPLEURI could inhibit the cardiac contraction force of the isolated toad heart and significantly slow down the heart rate.

关键词

柴胡/离体蟾蜍心脏/心脏收缩力/心率

Key words

RADIX BUPLEURI/ Isolated heart of toad/Cardiac contraction force/ Heart rate

分类

医药卫生

引用本文复制引用

付立波,付艳平,邓红..柴胡对蟾蜍离体心脏功能活动影响的研究[J].安徽农业科学,2011,39(35):21829-21830,2.

基金项目

吉林省教育厅"十一五"科学技术研究项目(吉教科合字2008第171号) (吉教科合字2008第171号)

长春市科技局资助课题[长科技合(2008255)号-08YJ38]. (2008255)

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