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九龙藤乙酸乙酯提取物清除自由基、镇痛抗炎作用研究

高杰 林炜鑫 钟屿云 卢少欢 简洁

安徽农业科学2011,Vol.39Issue(36):22305-22306,2.
安徽农业科学2011,Vol.39Issue(36):22305-22306,2.

九龙藤乙酸乙酯提取物清除自由基、镇痛抗炎作用研究

Study of the Ethyl Acetate Extract from Stem of Champion Bauhinia on Scavenging Free Radicals, Analgesia and Anti - inflammatory Effects

高杰 1林炜鑫 1钟屿云 1卢少欢 1简洁1

作者信息

  • 1. 桂林医学院,广西桂林541004
  • 折叠

摘要

Abstract

[ Objective ] The aim was to study the effects of the ethyl acetate extract from Stem of Champion Bauhinia on scavenging free radicals , analgesia and anti - inflammatory. [ Method] To investigate the cleaning and depressant effects of the ethyl acetate extract on free radicals by using the system of proceeding oxyradical (O2-·) and hydroxy radical ( · OH) in vitro. The analgesic effect and anti - inflammatory action were observed by using the mice writhing test, the hot - plate test and the model of mice ear swelling caused by xylol. [ Result] Compared with the control group, the ethyl acetate extract from Stem of Champion Bauhinia at low, middle and high concentrations (final concentrations were 5, 10, 20 mg/ml respectively) could scavenge O2-· and ·OH in a concentration - dependent manner (P <0, 05). Meanwhile, it increased the pain threshold of mice and decreased the ear swelling caused by xylo significantly. [Conclusion] The ethyl acetate extract has good effects on scavenging free radicals, analgesia and anti -inflammatory.

关键词

九龙藤乙酸乙酯提取物/抗自由基/镇痛/抗炎

Key words

Ethyl acetate extract from Stem of Champion Bauhinia/ Scavenging free radicals/ Analgesia/ Anti - inflammatory

分类

医药卫生

引用本文复制引用

高杰,林炜鑫,钟屿云,卢少欢,简洁..九龙藤乙酸乙酯提取物清除自由基、镇痛抗炎作用研究[J].安徽农业科学,2011,39(36):22305-22306,2.

基金项目

广西教育厅课题(201010LX337). (201010LX337)

安徽农业科学

0517-6611

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