安徽农业科学2011，Vol.39Issue(36)：22346-22347,2.
鸡大肠杆菌重组1型菌毛疫苗的免疫原性
Immunogenicity of Vaccine against Recombinant Type 1 Pilus of Avian Escherichia coli in Chickens
摘要
Abstract
[Objective] To prepare vaccine against recombinant type 1 pilus protein of avian Escherichia coli and to detect its immunogenicity in chickens. [Method] The type 1 pilus was respectively isolated from the recombinant bacteria CZYR10 strain and wild avian Escherichia coli YR(018) strain and used to prepare oil - emulsified vaccine. The immunogenicity of the developed vaccine was detected in chickens using challenge test. [Result] The recombinant type 1 pilus protein had immunoprotective efficacy. The recombinant type 1 pilus protein had weaker protective efficacy then the isolated type 1 pilus protein, but the difference was not significant. [Conclusion] The study provides a reference for immunization and control of chicken colibacillosis.关键词
鸡大肠杆菌/重组1型菌毛疫苗/免疫原性。Key words
Avian Escherichia coli/ Recombinant type 1 pilus/ Immunogenicity分类
农业科技引用本文复制引用
甘黎明,蒋加进,陈钟鸣,张志成,戴鼎震..鸡大肠杆菌重组1型菌毛疫苗的免疫原性[J].安徽农业科学,2011,39(36):22346-22347,2.基金项目
江苏省自然科学基金资助(BK2008059). （BK2008059）
