安徽农业科学Issue(5):2566-2569,2573,5.
小GTPase蛋白家族的研究进展
Research Progress of the Small GTPase Family
摘要
Abstract
[Objective] The aim was to summarize the research progress of small GTPase family,to provide reference for deeply analyzing the structure .function and its molecular action model of small GTPase. [ Methods] The structure,mechanism of action and classification of small GTPase were introduced,moreover,the biological functions of each subfamily were summarized emphatically. [Result] The small GTPase is a large superfamily in eukaryotes,which contains more than 100 members. It is classified into Ras,Rho,Rab,Sar/Arf and Ran five distinct families,each of them participate in various physiological processes of organism such as cytoslceletal reorganization,gene expression,cell wall synthesis, vesicle trafficking,nucleocytoplasmic trafficking, microtubules formation,yeast budding process,spindle assembly and polarity of the cell growth. [Conclusion ] The small GTPase has many members, its molecular action mechanism and regulatory complex network remain to be further studied.关键词
小G蛋白/生物学功能Key words
Small GTPase/ Biological function分类
生物科学引用本文复制引用
石佰丽,吕梦燕,赵秋雁..小GTPase蛋白家族的研究进展[J].安徽农业科学,2012,(5):2566-2569,2573,5.基金项目
国家自然科学基金面上项目(31070221). (31070221)