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小GTPase蛋白家族的研究进展

石佰丽 吕梦燕 赵秋雁

安徽农业科学Issue(5):2566-2569,2573,5.
安徽农业科学Issue(5):2566-2569,2573,5.

小GTPase蛋白家族的研究进展

Research Progress of the Small GTPase Family

石佰丽 1吕梦燕 2赵秋雁1

作者信息

  • 1. 东北林业大学园林学院,黑龙江哈尔滨 150040
  • 2. 东北林业大学林木遗传育种国家重点实验室,黑龙江哈尔滨 150040
  • 折叠

摘要

Abstract

[Objective] The aim was to summarize the research progress of small GTPase family,to provide reference for deeply analyzing the structure .function and its molecular action model of small GTPase. [ Methods] The structure,mechanism of action and classification of small GTPase were introduced,moreover,the biological functions of each subfamily were summarized emphatically. [Result] The small GTPase is a large superfamily in eukaryotes,which contains more than 100 members. It is classified into Ras,Rho,Rab,Sar/Arf and Ran five distinct families,each of them participate in various physiological processes of organism such as cytoslceletal reorganization,gene expression,cell wall synthesis, vesicle trafficking,nucleocytoplasmic trafficking, microtubules formation,yeast budding process,spindle assembly and polarity of the cell growth. [Conclusion ] The small GTPase has many members, its molecular action mechanism and regulatory complex network remain to be further studied.

关键词

小G蛋白/生物学功能

Key words

Small GTPase/ Biological function

分类

生物科学

引用本文复制引用

石佰丽,吕梦燕,赵秋雁..小GTPase蛋白家族的研究进展[J].安徽农业科学,2012,(5):2566-2569,2573,5.

基金项目

国家自然科学基金面上项目(31070221). (31070221)

安徽农业科学

0517-6611

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