安徽农业科学Issue(5)：2720,2723,2.
ICR小鼠肥胖模型的建立以及肥胖指标和脂肪组织形态学比较
Establishment of the Obesity Model of ICR Mice and the Comparison of the Obesity Index and Morphology of Adipose Tissue
摘要
Abstract
[ Objective ] The research aimed to establish the obesity model of ICR mice and compare the morphological differences of adipose tissue between obese mice and control mice. [ Method]Taking ICR mice as the study objects,the obesity model was established by feeding high-fat diet. The body weight, wet weight of adipose tissue and fat coefficient of ICR mice were determined and the morphological comparison of adipose tissue was made. [ Result ] The success rate of the obesity model of female and male mice were 16.67% and 66.67% respectively. After ICR mice were fed with high - fat diet, the body weight, wet weight of adipose tissue and fat coefficient of obese mice had extremely significant difference with that in control group(P<0.01 ) and the volume of adipose cells in adipose mice were obviously increased. [Conclusion]The research provided basis for the establishment of obesity model of ICR mice and the morphological study of adipose tissue.关键词
ICR小鼠/肥胖模型/脂肪组织/形态学Key words
ICR mice/ Obesity model/ Adipose tissue/ Morphology分类
生物科学引用本文复制引用
陈粉粉,郭爱伟,周杰珑,贺学龙,李皓..ICR小鼠肥胖模型的建立以及肥胖指标和脂肪组织形态学比较[J].安徽农业科学,2012,(5):2720,2723,2.基金项目
云南省重点学科野生动植物保护与利用课题(XKZ200901). （XKZ200901）
