摘要
Abstract
Objective To perform the serological researches on Hashimoto disease（HT） complicated with thyroid nodule to be useful to make sure the clinical diagnosis,make it easier to choose an appropriate therapeutic plan and more reasonable operation,decrease the recurrence rate,the carcinogenesis rate and the thyroid insufficiency resulting from the too little thyroid tissue survived after the operation.Method The patients who underwent the thyroid surgery due to the thyroid nodule were diagnosed as HT complicated with thyroid nodule（thyroidcarcinoma,nodular goiter,thyroid adenoma） with the pathological method after the operation were taken as group A,and non-HT patients as group B.The results from the TGAB,TMAB serological tests before the operation were compared and analyzed to discuss whether the TGAB,TMAB testing result was specifically related to the diagnosis of Hashimoto thyroiditis and HT complicated with thyroid nodule（thyroidcarcinoma,nodular goiter,thyroid adenoma）.Results The TGAB and TMAB testing values of 46 cases in group A were positive and the positive rate was 71.9%,and the values of 37 cases in group B were positive and the positive rate was 14.2%.The statistic analysis showed that the data were in a normal distribution and the difference between group A and B was P0.05,indicating that the difference was significant.The differences among the various diseases in group A were P0.05,there was no significance in statistics.Conclusion The TGAB and TMAB test result show that it is conducive to the study on the difference in TGAB and TMAB levels between the patients HT complicated thyroid nodule and non-HT in statistics,and instructive to the thyroid operation.关键词
桥本氏甲状腺炎/甲状腺球蛋白抗体/甲状腺微粒体抗体Key words
Hashimoto thyroiditis/TGAB/TMAB分类
医药卫生
