北京生物医学工程2012,Vol.31Issue(1):10-15,6.DOI:10.3969/ j.issn. 1002-3208(2012)01.03.
脑组织射频消融的有限元仿真与分析
Finite element simulation analysis of radiofrequency ablation in brain
摘要
Abstract
Objective To simulate the temperature distribution during radiofrequency ablation ( RFA) of intracranial lesion by the finite element method ( FEM ) . This thermotherapy might improve the treatment effectiveness of the RFA in intracranial nidus. Methods Two finite element models including the constant electrical conductivity model and the temperature-dependent conductivity model were built, and the key parameters including central temperature , electric field intensity , heat flux , specific absorption rate ( SAR ) and lesion size were compared. Results In the case of the temperature-dependent conductivity, the lower electric field intensity , the higher electric current density, the higher central temperature , and the bigger lesion size were obtained. The impact of the temperature-dependent conductivity on the radiofrequency ablation operation was great, especially when the central temperature was near to 100℃ . Conclusions The temperature-dependent parameters provided important clinical reference values in the intracranial radiofrequency ablation operation.关键词
颅内病灶/射频消融/有限元法/仿真分析/比吸收率Key words
intracranial nidus/ radiofrequency ablation/ finite element method/ simulation analysis/ specific absorption rate分类
医药卫生引用本文复制引用
洪焦,高宏建,吴水才..脑组织射频消融的有限元仿真与分析[J].北京生物医学工程,2012,31(1):10-15,6.基金项目
北京市自然科学基金(3112005)资助 (3112005)