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脑组织射频消融的有限元仿真与分析

洪焦 高宏建 吴水才

北京生物医学工程2012,Vol.31Issue(1):10-15,6.
北京生物医学工程2012,Vol.31Issue(1):10-15,6.DOI:10.3969/ j.issn. 1002-3208(2012)01.03.

脑组织射频消融的有限元仿真与分析

Finite element simulation analysis of radiofrequency ablation in brain

洪焦 1高宏建 1吴水才1

作者信息

  • 1. 北京工业大学生命科学与生物工程学院,北京100124
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摘要

Abstract

Objective To simulate the temperature distribution during radiofrequency ablation ( RFA) of intracranial lesion by the finite element method ( FEM ) . This thermotherapy might improve the treatment effectiveness of the RFA in intracranial nidus. Methods Two finite element models including the constant electrical conductivity model and the temperature-dependent conductivity model were built, and the key parameters including central temperature , electric field intensity , heat flux , specific absorption rate ( SAR ) and lesion size were compared. Results In the case of the temperature-dependent conductivity, the lower electric field intensity , the higher electric current density, the higher central temperature , and the bigger lesion size were obtained. The impact of the temperature-dependent conductivity on the radiofrequency ablation operation was great, especially when the central temperature was near to 100℃ . Conclusions The temperature-dependent parameters provided important clinical reference values in the intracranial radiofrequency ablation operation.

关键词

颅内病灶/射频消融/有限元法/仿真分析/比吸收率

Key words

intracranial nidus/ radiofrequency ablation/ finite element method/ simulation analysis/ specific absorption rate

分类

医药卫生

引用本文复制引用

洪焦,高宏建,吴水才..脑组织射频消融的有限元仿真与分析[J].北京生物医学工程,2012,31(1):10-15,6.

基金项目

北京市自然科学基金(3112005)资助 (3112005)

北京生物医学工程

OACSTPCD

1002-3208

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