李洁 1杜续 1杨兴智 1钟文 1龚光明 2亓鲁光 2文後2
作者信息
- 1. 成都中医药大学,四川成都610075
- 2. 成都中医药大学第一附属医院内分泌科,四川成都 610072
- 折叠
摘要
Abstract
Objective: To investigate clinical characteristics and the chronic complications status of newly-diagnosed type 2 dia betes mellitus, and discuss the relationship between the Chinese medicine patterns and the chronic complications of newly-diagnosed type 2 diabetes mellitus. Method According to the researchs case integrated and eliminated standards, in terms of unitive survey form to investigate the Chengdu University of Traditional Chinese Medicine affiliated hospital from October, 2008 to October, 2010 Department of Endocrinology outpatient and inpatient of newly-diagnosed type 2 diabetes mellitus, gather their clinical and the Chinese syndrome differentiation materials, group whether there is complications, to do the related statistics analysis, comparing differences between two groups. Result In 188 newly-diagnosed type 2 diabetes mellitus patients which are integrated, 111 patients exist at least one kind of chronic complications, the morbidity reaches high as 59. 04%. In the chronic complications group, the morbidity of combination with lipid metabolic disorder is highest, reaching as 61. 3%. The Chinese pattern of syndrome of newly-diagnosed type 2 diabetes mellitus patients is still mainly qi and yin deficiency, deficient syndrome ratio obviously is higher than sufficient syndrome, the frequency of the qi deficient syndrome is above the yin deficient syndrome, the frequency of excess heat syndrome is less than 20% , deficient syndrome between two groups have no significant difference, in sufficient syndrome, both P value of phlegm-damp syndromeand blood stasis syn drome is smaller than 0.01, have the significant difference; Diabetic great vessel pathological changes have positive correlation with qi deficiency syndrome, yin deficiency syndrome, the blood stasis syndrome (r =0. 102、 0. 107 、 0. 118, P <0. 05) , phlegm-damp syndrome significantly (r =0. 166, P <0. 01) ; Diabetes microvascular pathological changes have positive correlation with qi defi ciency syndrome (r = 0. 113, P < 0. 05), the blood stasis syndrome significantly ( r = 0. 196, P<0.01) . Conclusions The the mor bidity of newly-diagnosed type 2 diabetes mellitus chronic complications is high, awareness rate is low. "The sugar toxin" and "the lipid toxin" possibly is the important factor which accelerate occurrence of chronic complications, the prevention should pay great atten tion to control the multiple risk factors. Characteristics of diabetic chronic complications is " asthenia in origin and excess in superficiali ty" . "Deficiency、 blood stasis" are throughout diabetes and its chronic complications. "Qi and yin deficiency, hlegm-damp and blood stasis blocking venation" possibly is the common pathologic foundation causing the diabetic chronic complications.关键词
2型糖尿病/新诊断/慢性并发症/中医证型/早期防治Key words
Type 2 diabetes mellitus/ newly-diagnosed/ chronic complications/ Chinese patterns of syndrome/ early prevention and treatment分类
医药卫生
