重庆医学2012，Vol.41Issue(6)：550-551,2.DOI:10.3969/j.issn.1671-8348.2012.06.012
阿托伐他汀治疗急性缺血性卒中患者颈动脉粥样硬化斑块的临床研究
Clinical study of atorvastatin for treating carotid artery arteriosclerosis plaque in patients with ischemic stroke
焦岩 1徐江涛1
作者信息
- 1. 兰州军区乌鲁木齐总医院神经内科,乌鲁木齐,830000
- 折叠
摘要
Abstract
Objective To observe the clinical efficacy of atorvastatin on treating carotid artery arteriosclerosis plaque in the patients with ischemic stroke. Methods 120 patients with ischemic stroke complicating carotid artery arteriosclerosis plaque were randomly divided into the treatment group (n = 60) and the control group(n = 60). Both two groups were treated with routine methods. The treatment group was added with atorvastatin at the same time. The change of intima-media thickness(IMT) of carotid artery, the area of carotid atherosclerotic plaque, the changes in blood lipids and adverse reactions were observed before and after treatment between the two groups. Results IMT of carotid artery and the area of carotid atherosclerotic plaque were significantly reduced in two groups (P<0. 05 or P<0. 01). The treatment group had more effective than the control group(P<0. 05). After treatment the levels of serum total cholesterol(TC) , triglyceride(TG) and low-density lipoprotein cholesterol(LDL-C) were decreased obviously,high density lipoprotein cholesterol(HDL-C) was risen up obviously in the treatment group (P<0. 05 or P<0. 01). The blood lipid levels showed no statistical difference before and after treatment in the control group(P>0. 05). Conclusion Atorvastatin could releive atherosclerosis obviously,reduce plaque area,regulate blood lipid and prevent the occurrence of stroke events.关键词
动脉粥样硬化/缺血性卒中/阿托伐他汀Key words
arteriosclerosis/ischemic stroke/atorvastatin引用本文复制引用
焦岩,徐江涛..阿托伐他汀治疗急性缺血性卒中患者颈动脉粥样硬化斑块的临床研究[J].重庆医学,2012,41(6):550-551,2.
