重庆医学2012，Vol.41Issue(6)：567-568,2.DOI:10.3969/j.issn.1671-8348.2012.06.019
白芍总苷对寻常性银屑病患者血清瘦素及IL-18水平的影响
Effects of total glucosides of paeony on serum level of leptin and IL-18 in patients with psoriasis vulgaris
摘要
Abstract
Objective To observe the influence of total glucosides of paeony (TGP) on the serum leptin and lnterleukin-18(IL-18) levels in the patients with psoriasis vulgaris,and to discuss its functional mechanism. Methods The serum leptin and interleu-kin-18 levels before and after treatment with TGP in 70 patients with psoriasis vulgaris were detected by RIA and KLISA respectively. Results The serum leptin and interleukin-18 levels before treatment in the patients with psoriasis vulgaris were significantly higher than those after treatment and in the control group(P<0. 05). Compared with before treatment, their serum levels after TGP treatment were also significantly reduced(P<0. 05). Conclusion TGP may play the therapeutic role through inhibiting the secretion of serum leptin and interleukin-18.关键词
白芍总苷/寻常性银屑病/瘦素/白细胞介素18Key words
total glucosides of paeony/ psoriasis vulgaris/leptin/ interleukin-18引用本文复制引用
杜宇,廖勇梅,杨西群,颜丹,熊霞..白芍总苷对寻常性银屑病患者血清瘦素及IL-18水平的影响[J].重庆医学,2012,41(6):567-568,2.基金项目
四川省卫生厅课题计划项目(100265). （100265）
