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Nasopharyngeal adenoid cystic carcinoma: magnetic resonance imaging features in ten cases

Xue-Wen Liu Pei-Hong Wu Chuan-Miao Xie Hui Li Rong Zhang Zhi-Jun Geng Yun-Xian Mo Jing Zhao Mu-Yan Cai Yan-Chun Lv

癌症(英文版)2012,Vol.31Issue(1):19-28,10.
癌症(英文版)2012,Vol.31Issue(1):19-28,10.DOI:10.5732/cjc.011.10242

Nasopharyngeal adenoid cystic carcinoma: magnetic resonance imaging features in ten cases

Nasopharyngeal adenoid cystic carcinoma: magnetic resonance imaging features in ten cases

Xue-Wen Liu 1Pei-Hong Wu 2Chuan-Miao Xie 1Hui Li 2Rong Zhang 1Zhi-Jun Geng 2Yun-Xian Mo 1Jing Zhao 2Mu-Yan Cai 1Yan-Chun Lv2

作者信息

  • 1. State Key Laboratory of Oncology in South China,Guangzhou, Guangdong 510060, P. R. China
  • 2. Medical Imaging and Minimally Invasive Interventional Center
  • 折叠

摘要

Abstract

Nasopharyngeal adenoid cystic carcinoma (NACC) is a rare malignancy with high local invasiveness.To date,there is no consensus on the imaging characteristics of NACC.To address this,we retrospectively reviewed 10 cases of NACC and summarized the magnetic resonance imaging (MRI) features.MR images of 10 patients with histologically validated NACC were reviewed by two experienced radiologists.The location,shape,margin,signal intensity,lesion texture,contrast enhancement patterns,local invasion,and cervical lymphadenopathy of all tumors were evaluated.Clinical and pathologic records were also reviewed.No patients were positive for antibodies against Epstein-Barr virus (EBV).The imaging patterns of primary tumors were classified into two types as determined by location,shape,and margin.Of all patients,7 had tumors with a type 1 imaging pattern and 3 had tumors with a type 2 imaging pattern.The 4 tubular NACCs were all homogeneous tumors,whereas 3 (60%) of 5 cribriform NACCs and the sole solid NACC were heterogeneous tumors with separations or central necrosis on MR images.Five patients had perineural infiltration and intracranial involvement,and only 2 had cervical lymphadenopathy.Based on these results,we conclude that NACC is a local,aggressive neoplasm that is often negative for EBV infection and associated with a low incidence of cervical lymphadenopathy.Furthermore,MRI features of NACC vary in locations and histological subtypes.

关键词

Neoplasm of the nasopharynx/adenoid cystic carcinoma/magnetic resonance imaging (MRI)

Key words

Neoplasm of the nasopharynx/adenoid cystic carcinoma/magnetic resonance imaging (MRI)

引用本文复制引用

Xue-Wen Liu,Pei-Hong Wu,Chuan-Miao Xie,Hui Li,Rong Zhang,Zhi-Jun Geng,Yun-Xian Mo,Jing Zhao,Mu-Yan Cai,Yan-Chun Lv..Nasopharyngeal adenoid cystic carcinoma: magnetic resonance imaging features in ten cases[J].癌症(英文版),2012,31(1):19-28,10.

癌症(英文版)

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1000-467X

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